別名: FTO;KIAA1752;Alpha-ketoglutarate-dependent dioxygenase FTO;Fat mass and obesity-associated protein
Organism-1: 人
基因ID-1: 79068
SwissProt-1: Q9C0B1
Organism-2: Mouse
基因ID-2: 26383
SwissProt-2: Q8BGW1
Organism-3: Rat
基因ID-3: 291905
SwissProt-3: Q2A121
細(xì)胞定位: Cytoplasm, Nucleus
組織表達(dá): Ubiquitously expressed, with relatively high expression in adrenal glands and brain; especially in hypothalamus and pituitary (PubMed:17434869, PubMed:17496892). Highly expressed in highly expressed in acute myeloid leukemias (AML) with t(11;11)(q23;23) with KMT2A/MLL1 rearrangements, t(15;17)(q21;q21)/PML-RARA, FLT3-ITD, and/or NPM1 mutations (PubMed:28017614).
別名: FTO;KIAA1752;Alpha-ketoglutarate-dependent dioxygenase FTO;Fat mass and obesity-associated protein
Organism-1: 人
基因ID-1: 79068
SwissProt-1: Q9C0B1
Organism-2: Mouse
基因ID-2: 26383
SwissProt-2: Q8BGW1
Organism-3: Rat
基因ID-3: 291905
SwissProt-3: Q2A121
細(xì)胞定位: Cytoplasm, Nucleus
組織表達(dá): Ubiquitously expressed, with relatively high expression in adrenal glands and brain; especially in hypothalamus and pituitary (PubMed:17434869, PubMed:17496892). Highly expressed in highly expressed in acute myeloid leukemias (AML) with t(11;11)(q23;23) with KMT2A/MLL1 rearrangements, t(15;17)(q21;q21)/PML-RARA, FLT3-ITD, and/or NPM1 mutations (PubMed:28017614).
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