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STIM2 rabbit pAb
商品貨號： PLA021563
適 應(yīng) 性： 人,小鼠
WB IHC
￥600元
規(guī)格：
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MSDS
說明書
商品描述
  • 基因名稱： STIM2 KIAA1482
  • 蛋白名稱： Stromal interaction molecule 2
  • Human_gene_id： 57620
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57620
  • Human_swiss_prot_no： Q9P246
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9P246/entry
  • Mouse_gene_id： 116873
  • Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=116873
  • Mouse_swiss_prot_no： P83093
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P83093/entry
  • 特異性： This antibody detects endogenous levels of STIM2 at Human, Mouse
  • 組成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000 IHC 1:50-200
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Stromal interaction molecule 2
  • 分子量： 82kD
  • 功能： Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca(2+) influx.
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Dynamically translocates from a uniform endoplasmic reticulum distribution to punctual endoplasmic reticulum-plasma membrane junctions in response to decrease in endoplasmic reticulum Ca(2+) concentration.
  • 組織表達： Expressed in all tissues and tumor cell lines examined.
  • 科研貨號： PLA021563
STIM2 rabbit pAb
Catalog No PLA021563
Product information
  • 基因名稱： STIM2 KIAA1482
  • 蛋白名稱： Stromal interaction molecule 2
  • Human_gene_id： 57620
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57620
  • Human_swiss_prot_no： Q9P246
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9P246/entry
  • Mouse_gene_id： 116873
  • Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=116873
  • Mouse_swiss_prot_no： P83093
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P83093/entry
  • 特異性： This antibody detects endogenous levels of STIM2 at Human, Mouse
  • 組成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000 IHC 1:50-200
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Stromal interaction molecule 2
  • 分子量： 82kD
  • 功能： Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca(2+) influx.
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Dynamically translocates from a uniform endoplasmic reticulum distribution to punctual endoplasmic reticulum-plasma membrane junctions in response to decrease in endoplasmic reticulum Ca(2+) concentration.
  • 組織表達： Expressed in all tissues and tumor cell lines examined.
  • 科研貨號： PLA021563
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