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Total AIRE Cell-Based Colorimetric ELISA Kit
商品貨號： PLA001786
適 應(yīng) 性： 人,小鼠
ELISA
￥600元
規(guī)格：
在線咨詢
MSDS
說明書
商品描述
  • 發(fā)貨日期： 14
  • 基因名稱： AIRE
  • Human_gene_id： 326
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=326
  • Human_swiss_prot_no： O43918
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/O43918/entry
  • Mouse_swiss_prot_no： Q9Z0E3
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9Z0E3
  • 儲存： 2-8°C/6 months
  • 說明書： KA3991C.pdf
  • 其他名稱： Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein)
  • 功能： transcription,?regulation of transcription, DNA-dependent,?immune response,?humoral immune response,?regulation of transcription,?regulation of RNA metabolic process,
  • 相關(guān)產(chǎn)品： YT0154,YT0153,YP0458,KA3991C,KA1739C
  • 細胞定位： Nucleus . Cytoplasm . Predominantly nuclear but also cytoplasmic (PubMed:11274163, PubMed:14974083). Found in nuclear body-like structures (dots) and in a filamentous vimentin-like pattern (PubMed:11274163, PubMed:14974083, PubMed:26084028). Associated with tubular structures (PubMed:11274163, PubMed:14974083). .
  • 組織表達： Widely expressed. Expressed at higher level in thymus (medullary epithelial cells and monocyte-dendritic cells), pancreas, adrenal cortex and testis. Expressed at lower level in the spleen, fetal liver and lymph nodes. In secondary lymphoid organs, expressed in a discrete population of bone marrow-derived toleregenic antigen presenting cells (APCs) called extrathymic AIRE expressing cells (eTAC)(at protein level) (PubMed:23993652). Isoform 2 and isoform 3 seem to be less frequently expressed than isoform 1, if at all.
  • 科研貨號： PLA001786
Total AIRE Cell-Based Colorimetric ELISA Kit
Catalog No PLA001786
Product information
  • 發(fā)貨日期： 14
  • 基因名稱： AIRE
  • Human_gene_id： 326
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=326
  • Human_swiss_prot_no： O43918
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/O43918/entry
  • Mouse_swiss_prot_no： Q9Z0E3
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9Z0E3
  • 儲存： 2-8°C/6 months
  • 說明書： KA3991C.pdf
  • 其他名稱： Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein)
  • 功能： transcription,?regulation of transcription, DNA-dependent,?immune response,?humoral immune response,?regulation of transcription,?regulation of RNA metabolic process,
  • 相關(guān)產(chǎn)品： YT0154,YT0153,YP0458,KA3991C,KA1739C
  • 細胞定位： Nucleus . Cytoplasm . Predominantly nuclear but also cytoplasmic (PubMed:11274163, PubMed:14974083). Found in nuclear body-like structures (dots) and in a filamentous vimentin-like pattern (PubMed:11274163, PubMed:14974083, PubMed:26084028). Associated with tubular structures (PubMed:11274163, PubMed:14974083). .
  • 組織表達： Widely expressed. Expressed at higher level in thymus (medullary epithelial cells and monocyte-dendritic cells), pancreas, adrenal cortex and testis. Expressed at lower level in the spleen, fetal liver and lymph nodes. In secondary lymphoid organs, expressed in a discrete population of bone marrow-derived toleregenic antigen presenting cells (APCs) called extrathymic AIRE expressing cells (eTAC)(at protein level) (PubMed:23993652). Isoform 2 and isoform 3 seem to be less frequently expressed than isoform 1, if at all.
  • 科研貨號： PLA001786
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