功能: proteolysis,?apoptosis,?induction of apoptosis,?cell death,?regulation of cell death,?positive regulation of cell death,programmed cell death,?induction of programmed cell death,?death,?regulation of apoptosis,?positive regulation of apoptosis,?regulation of programmed cell death,?positive regulation of programmed cell death,
細胞定位: Cytoplasm, cytosol . Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Mitochondrion . Inflammasome . Secreted . Predominantly localizes to the endoplasmic reticulum (ER). Association with the ER membrane requires TMEM214 (PubMed:15123740). Released in the extracellular milieu by keratinocytes following UVB irradiation (PubMed:22246630). .
組織表達: Widely expressed, including in keratinocytes and colonic and small intestinal epithelial cells (at protein level). Not detected in brain.
功能: proteolysis,?apoptosis,?induction of apoptosis,?cell death,?regulation of cell death,?positive regulation of cell death,programmed cell death,?induction of programmed cell death,?death,?regulation of apoptosis,?positive regulation of apoptosis,?regulation of programmed cell death,?positive regulation of programmed cell death,
細胞定位: Cytoplasm, cytosol . Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Mitochondrion . Inflammasome . Secreted . Predominantly localizes to the endoplasmic reticulum (ER). Association with the ER membrane requires TMEM214 (PubMed:15123740). Released in the extracellular milieu by keratinocytes following UVB irradiation (PubMed:22246630). .
組織表達: Widely expressed, including in keratinocytes and colonic and small intestinal epithelial cells (at protein level). Not detected in brain.
科研貨號: PLA001732
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